Endometrial cancer p53
Arch Gynecol Obstet ; 6 :Dec. SSTs are usually hormone inactive and tend to occur in the second and third decades of life.
The most common clinical symptom is menstrual irregularity. Tumour samples were collected, embedded in paraffin and stained with haematoxylin and eosin, periodic acid-Schiff PASand PAS with digestion, as well as immunohistochemically for vimentin, smooth muscle actin, desmin, CD 99, inhibin-α and the oestrogen and progesterone receptor.
The tumours ranged in size from 6 to 21 cm mean Macroscopically, eight tumours were solid and six were solid and cystic. All SSTs were well circumscribed with endometrial cancer p53 formation.
Spindle-shaped fibroblast-like cells and vacuolated theca-like cells were prominent. Blood vessels exhibited a hemangiopericytomatous pattern and boomerang-like features. Although inhibin-α, CD 99 and desmin staining may be a useful and reliable tool for SST diagnosis in problematic cases, an immunohistochemical panel will not discriminate from other tumours in the sex cord-stromal group.